Vitamin D3 + K2
- Contains 1,000 IU of vitamin D3 per daily dose , obtained from lichens
- In combination with vitamin K2 (MK-7, fermented) for optimal bioavailability
- Supports the normal function of bones, muscles and the immune system *
- Contributes to normal blood clotting and targeted calcium utilization *
- with high-quality MTC oil for higher bioavailability
*according to EU Regulation 1924/2006
- Estimated delivery Nov 25 - Nov 29
- High bioavailability due to high-quality nutrient forms
- Pure & vegan
- free from gluten, artificial colors and preservatives
- Scientifically tested formula – developed with medical expertise
- 1000 IU (500 IU/drop) easy to dose to meet all needs
PUROGYN Vitamin D3 & K2 – a powerful duo for bones, muscles and the immune system
PUROGYN Vitamin D3 & K2 (MK7) in combination with MCT oil unites two essential nutrients that work closely together in the body and are important for key functions.
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Vitamin D contributes to the normal absorption and utilization of calcium and phosphorus, to the maintenance of normal bones, teeth and muscles, and to the normal function of the immune system.
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Vitamin K contributes to the maintenance of normal bones and normal blood clotting.
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Together they support calcium metabolism: Vitamin D3 promotes the absorption of calcium from food, while vitamin K2 in its bioactive MK7 form helps to incorporate calcium into the bones.
The combination with MCT oil improves absorption, as both are fat-soluble and can therefore be optimally utilized.
Contents:
30 ml
Recommended intake:
1-3 drops
MTC oil, vitamin K2 MK/ All-Trans, vitamin D3 (cholecaliciferol)
| Inhalt | pro 2 Tropfen | % NRV* |
|---|---|---|
| Vitamin D3 (Cholecalciferol) | 50 µg (= 2 000 I.E.) | 1 000 % |
| Vitamin K2 (vitaMK7®) | 40 µg | 53 % |
*NRV = Nutrient Reference Value (Referenzmenge) gemäß EU-Verordnung 1169/2011.
Significance in different phases of a woman's life
- PMS & Menstruation : Studies are investigating possible links between vitamin D levels, mood, and cycle regulation. Adequate vitamin D levels also contribute to normal psychological and immune function.
- Desire to have children : Studies suggest that vitamin D may be associated with fertility and reproductive health. At the same time, vitamin D contributes to cell division – an important foundation for early development.
- Pregnancy & Breastfeeding : Vitamin D is needed for normal bone growth and development in children. Low vitamin D levels in mothers have been linked in studies to risks for the child's bone health. Vitamin K also supports the maintenance of normal bones.
- Perimenopause : During this phase, hormonal changes can affect bone metabolism. Studies suggest that an adequate supply of vitamins D and K2 supports bone density and muscle function and may also influence inflammatory processes.
- Menopause : With declining estrogen levels, the risk of osteoporosis increases. Studies suggest that the combined intake of vitamins D3 and K2 can strengthen bone health and contribute to vascular function. Some researchers see great potential here, which is currently being intensively investigated.
Studies and specialist literature
Below you will find an overview of scientific papers on vitamin D3 & K2 – categorized according to the life stages of women.
Desire to have children & fertility
- Parikh G. et al. (2010), Fertil Steril. Review article on vitamin D in PCOS: Low levels are common and associated with menstrual irregularities, insulin resistance, and impaired ovulation. Supplementation can positively influence hormonal parameters.
- Lerchbaum E., Rabe T. (2014), Curr Opin Obstet Gynecol. Vitamin D influences gene expression in the endometrium and ovaries; adequate levels are associated with better fertility and implantation rates.
- Franasiak JM et al. (2017), Reprod Biol Endocrinol. Women with optimal vitamin D status showed higher pregnancy rates after IVF treatments – indicating its importance for reproductive processes.
pregnancy
- Holick MF et al. (2011), J Clin Endocrinol Metab. Endocrine Society guideline: A serum level above 30 ng/mL is recommended. Inadequate supply is associated with preeclampsia, preterm births, and gestational diabetes.
- Aghajafari F. et al. (2013), BMJ. Meta-analysis of 31 studies with over 24,000 women shows: Low vitamin D levels increase the risk of preeclampsia, gestational diabetes and premature birth.
- Roth DE et al. (2018), Nutrients. Vitamin D supplementation improves maternal supply and can reduce the risk of premature birth and infection.
- Karras SN et al. (2015), Hormones. Emphasizes the importance of adequate vitamin D intake for bones, the immune system, and child development.
breastfeeding
- Hollis BW, Wagner CL (2015), Am J Clin Nutr. High maternal vitamin D3 intake (4,000–6,400 IU/day) can ensure the vitamin D status of the breastfed infant – an alternative to direct administration to the child.
- Innis SM (2014), Ann Nutr Metab. The vitamin D content of breast milk depends directly on maternal intake; relevant for the infant's bone and immune system.
- Weiler HA et al. (2020), Nutrients. Confirmed: High maternal doses significantly improve the infant's vitamin D levels.
PMS & hormonal well-being
- Abdi F. et al. (2019), Gynecol Endocrinol. Meta-analysis: Vitamin D supplementation significantly reduces overall PMS symptoms – especially irritability, fatigue, and breast tenderness.
- Khayat S. et al. (2016), Iran J Nurs Midwifery Res. Randomized study: 50,000 IU of vitamin D every two weeks for eight weeks led to significant relief of mood swings, headaches, and sleep disturbances.
- Jorde R., Grimnes G. (2016), Curr Opin Clin Nutr Metab Care. Vitamin D deficiency correlates with depressive symptoms; adequate supply can improve mental balance.
- Banaszewska B. et al. (2015), J Clin Endocrinol Metab. Vitamin D has hormone-regulating and anti-inflammatory effects – relevant for PMS and menstrual cycle problems.
- Masoumi SZ et al. (2016), Obstet Gynecol Sci. Combined administration of vitamin D and calcium reduced PMS symptom burden more than placebo.
Perimenopause & Menopause
- Bischoff-Ferrari HA et al. (2016), JAMA Intern Med. Vitamin D supplementation (800–2000 IU/day) reduces the risk of falls and supports muscle and bone function.
- Reid IR et al. (2014), Lancet. Meta-analysis. Significant improvements in bone density with regular vitamin D intake – especially important in postmenopausal women.
- Knapen MHJ et al. (2013), Osteoporos Int. Three-year study: Vitamin K2 (MK-7) improved bone density and elasticity in postmenopausal women.
- Vermeer C., Theuwissen E. (2021), Front Nutr. Vitamin K2 activates bone- and vessel-protecting proteins (osteocalcin, MGP); synergistic effect with D3 for bone and heart health.
Synergies of Vitamin D3 & K2
- Kanellakis S. et al. (2012), Nutrients. The combination of D3 + K2 improves calcium utilization and reduces markers of bone loss more effectively than D3 alone.
- Ushiroyama T. et al. (2012), J Nutr Sci Vitaminol. Vitamins D3 and K2 together activate osteocalcin and matrix Gla protein – important for bone formation and vascular protection.
- Pludowski P et al. (2019), Nutrients.
Central European guideline: Recommended vitamin D3 intake 800–2000 IU/day; balanced vitamin K2 intake is recommended to support calcium metabolism.
Notice
This literature review is for scientific information purposes only. It does not refer to PUROGYN products and does not replace medical advice.
